A Case of Cushing's syndrome with Oral Candidiasis

  • HAYASAKA Junichi
    Department of Dentistry, Oral and Maxillofacial Surgery, Jichi Medical School
  • JINBU Yoshinori
    Department of Dentistry, Oral and Maxillofacial Surgery, Jichi Medical School
  • ITO Hiroto
    Department of Dentistry, Oral and Maxillofacial Surgery, Jichi Medical School
  • KUSAMA Mikio
    Department of Dentistry, Oral and Maxillofacial Surgery, Jichi Medical School

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Other Title
  • 口腔カンジダ症を生じたクッシング症候群の1例

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Abstract

The patient was a 12-year-old male who complained of white patches in the oral mucosa. He showed a moon-face and difficulty in walking due to muscle hypofunction. Blood examination showed an elevated value of serum cortisol, suggesting Cushing's syndrome. Oral examination revealed poor oral hygiene condition, with white plaque in the buccal mucosa and tongue. Clinical diagnosis was oral candidiasis and Candida albicans was isolated from his oral mucosa by the cotton swab method. After instruction of oral hygiene techniques, gargle with Amphotericin B (Fungizone®) and medication of Trilostane (Desopan®), serum cortisol value decreased and candidiasis completely disappeared.

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