横行結腸間膜原発GIST(EGIST)の1例

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  • A CASE OF GASTROINTESTINAL STROMAL TUMOR (GIST) OF THE MESENTERY OF THE TRANSVERSE COLON

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A 68-year-old woman seen at another hospital because of abdominal distension in May 2000 was found having an elastic-hard tumor with the size of infant's head in the right abdomen. Ultrasonography and CT showed a multilocular cystic lesion, 20 cm in diameter, with a part of parenchymatous component, and another tumor 5 cm in diameter in the pelvis. Angiography showed only an expansively growing tumor and could not indicate growth of tumor vessels and accumulation of contrast material. The patient was operated on for treatment and diagnosis of the abdominal tumor. During surgery a soft tumor which was 25 cm in diameter and white in color and had smooth surface was identified in the mesentery of the transverse colon. And a solid tumor which was 5 cm in diameter and grayish white in color was present on the retroperitoneum in the pelvis. These tumors were removed. On histopathological and immunohistological studies, they were positive for c-kit, α-SMA, and desmin. Gastrointestinal stromal tumor (GIST) arisen in the mesentery of the transverse colon was diagnosed.<br>GIST arising in the extra-intestinal tissue is rare and is sometimes called EGIST. In this paper we present an analysis of accumulated cases from recent Japanese literature, together with some bibliographical consideration.

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