Leser‐Trelat徴候により発見された多発胃癌の1例

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  • A Case of Multifocal Gastric Cancer Detected by the Sign of Leser-Trelat

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The sign of Leser-Trélat is defined as seborrheic keratosis with pruritus characterized by rapidly increasing size and number. We report a case of multifocal early gastric cancer detected by the sign of Leser-Tré lat in the neck and chest. An 80-year-old man seen at the department of dermatology for rapidly spreading pruritus with and cervix and chest itching was suspected of the sign of Leser-Trélat, necesictating upper gastrointestinal endoscopy that indicated early gastric cancer. The distal gastrectomy specimen showed three independent early cancer foci. The man continues to be well and relapse free 4 years after surgery. Seborrheic keratosis characterized by pruritus rapidly increasing size and number should lead diagnosticians to suspect the sign of Leser-Tré lat and the possible existence of visceral organ malignancies.

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