Development of X-ray dark-field imaging and its approach to clinical application

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  • ANDO Masami
    Photon Factory, IMSS, KEK Department of Photo-Science, School of Advanced Studies, GUAS Department of Material Structure Studies, School of High Energy Accelerator Science, KEK
  • SUGIYAMA Hiroshi
    Photon Factory, IMSS, KEK Department of Photo-Science, School of Advanced Studies, GUAS

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Other Title
  • X線暗視野法(DFI)の開発と臨床応用への道
  • Xセンアンシヤホウ DFI ノ カイハツ ト リンショウ オウヨウ エ ノ ミチ

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Abstract

<p>In clinics one utilizes four types of imaging, namely, X-ray, ultrasound, PET (positron emission tomography) and MRI (magnetic resonance imaging). These techniques and their diagnostic capabilities are improving. Nevertheless visualizing soft tissues are not easy. We have come up with an idea of X-ray dark-field imaging that can provide us with images only due to refraction. One does not need mathematical procedure to deduce refraction component in this method. A test is under way to verify usefulness of this DFI. A field size of up to 90 mm in square has been achieved. When applied to human joints, and breast cancer phantom and human sliced breast cancer specimens this method can clearly visualize thus far invisible structure. The spatial resolution on the order of 10 microns or better is achieved. This system is approaching clinical trial. In this note we describe our recent results.</p>

Journal

  • Oyo Buturi

    Oyo Buturi 74 (4), 446-452, 2005-04-10

    The Japan Society of Applied Physics

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