騒音性難聴２症例の側頭骨病理所見

• 中本 吉紀

  帝京大学医学部付属病院耳鼻咽喉科

• 飯野 ゆき子

  帝京大学医学部付属病院耳鼻咽喉科

• 小寺 一興

  帝京大学医学部付属病院耳鼻咽喉科

書誌事項

タイトル別名

• Temporal Bone Histopathology of Noise-induced Hearing Loss
• ソウオンセイ ナンチョウ 2 ショウレイ ノ ソクトウコツ ビョウリ ショケン

抄録

To examine the relationship between hearing and changes in the inner ear, we investigated human temporal bone specimens from 2 patients with noise-induced hearing loss and prepared audio-cytocochleograms as described by Schuknecht et al.<BR>Patient 1 was a 50-year-old male who died of thyroid cancer and had worked at a printing house for 38 years. Patient 2 was a 58-year old male who died of maxillary sinus cancer and had worked in construction for 22 years. A puretone audiogram showed high-tone sensorineural hearing loss with c⁵-dip-type hearing disorder in both ears in Patient 1, and a high-tone abrupt form of sensorineural hearing loss in Patient 2. Pathological examination of the temporal bone revealed degeneration and disappearance of the organ of Corti at the basal turn and disappearance of cochlear neurons in both patients. Audio-cytocochleograms revealed hearing disorder consistent with the changes in the inner ear in both patients. Marked degeneration and disappearance of the organ of Corti and stria vascularis were present in patient 1.<BR>It is generally known that disorders of the organ of Corti for a long period is involved in the etiology of noise-induced hearing loss. This degeneration of the organ of Corti is produced at a basilar membrane with the maximum amplitude related to exposure to noise according to a physical and mechanical factors.<BR>Moreover, animal experiments have shown that exposure to noise decrease cochlear blood flow. In Patient 1 both the organ of Corti and the stria vascularis exhibited degeneration, suggesting that not only physical and mechanical factors but a cochlear circulatory disorder related to exposure to noise was involved in the etiology of the pathological changes in the temporal bone related to noise-induced hearing loss.

収録刊行物

• 日本耳鼻咽喉科学会会報

  日本耳鼻咽喉科学会会報 108 (2), 172-181, 2005

  一般社団法人 日本耳鼻咽喉科頭頸部外科学会

キーワード

• 騒音性難聴
• 側頭骨病理
• 血管条変性
• 蝸牛内循環

詳細情報

• CRID: 1390001205007085312
• NII論文ID: 10015568469
• NII書誌ID: AN00191551
• DOI: 10.3950/jibiinkoka.108.172
• ISSN: 18830854
• ISSN: 00306622
• NDL書誌ID: 7289603
• PubMed: 15765731
• Web Site: http://id.ndl.go.jp/bib/7289603
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I7289603
• Web Site: https://search.jamas.or.jp/link/ui/2005097385
• 本文言語コード: ja
• データソース種別:
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