Von Recklinghausen病に十二指腸カルチノイドを合併した1例―本邦報告例18例の文献的考察―

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  • A Case of Duodenal Carcinoid Tumor in the Patient with Von Recklinghausen's Disease

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A 52-year-old man had café au lait spots covering his body from infancy. His brother had undergone gastrectomy for gastric carcinoma and had von Recklinghausen's disease. In July 1992, gastroscopy showed an submucosal tumor near the duodenal papilla. In March 1998, SMT was redetected. He was examined further by abdominal computed tomography, abdominal ultrasonography, endoscopic retrograde cholangiopancreaticography, and angiography, but we could not determine whether SMT was malignant. Five years later, when he developed abdominal examination yieled a diagnosis of carcinoid tumor for SMT. We conducted pylorus-preserving pancreatoduodenectomy on December 11, 2003. The 25×25×23mm resected tumor was located near the papilla in the second part of the duodenum. He had lymph node metastases and the tumor showed mitotic figures with vascular invasion on microscopic examination, which suggested high-grade malignancy.

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