ＳＢＪ‐ＰＲＯ２の歯垢除去等に対する臨床試験（治験）

DOI 被引用文献1件 参考文献25件

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  • A Clinical Trial of SBJ-PRO2 for Dental Plaque Removal.

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While dentifrices containing triclosan at 0.02% have conventionally been used in Japan, we experimentally prepared a dentifrice (SBJ-PRO2) containing triclosan at 0.3%. Thus, we planned and conducted a general clinical trial to investigate its effects in eliminating plaque and in reducing gingival inflammation. Efficacy and safety of a long-term use of dentifrices with a triclosan content of 0.3% have been reported abroad. In this study, we investigated its efficacy and safety during short-term use.<BR>A 4-week clinical trial was conducted an 70 patients between 20 and 65 years of age. As a result, the plaque index improved by 84.1%, and the gingivitis index improved by 89.9%. Concerning safety, there were no adverse events or adverse drug reactions.<BR>These results suggested that a dentifrice with a triclosan content of 0.3% is safe, usetul, and effective in eliminating plaque, and it provides a tool for self-prophylaxis against periodontal diseases.

収録刊行物

  • 歯科薬物療法

    歯科薬物療法 20 (1), 23-31, 2001

    日本歯科薬物療法学会

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