A CASE OF BONE MARROW CARCINOMATOSIS OF BREAST CANCER
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- MURAKAMI Masahiro
- Department of Surgery, NTT West Osaka Hospital
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- NAKANO Yoshiaki
- Department of Surgery, NTT West Osaka Hospital
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- ONISHI Tadashi
- Department of Surgery, NTT West Osaka Hospital
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- TONO Takeshi
- Department of Surgery, NTT West Osaka Hospital
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- YANO Hiroshi
- Department of Surgery, NTT West Osaka Hospital
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- MONDEN Takushi
- Department of Surgery, NTT West Osaka Hospital
Bibliographic Information
- Other Title
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- 乳癌骨髄癌症の1例
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Abstract
This paper deals with a 55-year-old woman with bone marrow carcinomatosis of breast cancer. The patient had undergone a partial mastectomy for left breast cancer in June 1999, which was located in the left D area, was 15×15mm in diameter, invasive ductal carcinoma, scirrous type, f, tl, T1NXM1 stage IV, and both ER and PgR positive. Cancerous pleuritis and multiple bone metastases were found and systemic hormone therapy with toremifene and chemotherapy with cyclophosphamide, methotrexate, and 5-FU (VMF) were conducted. In October 2001, she was admitted to the hospital because of acute hemolytic anemia. Bone marrow examination to explore the cause revealed metastasis of adenocarcinoma. We thus diagnosed the case as microangiopathic hemolytic anemia (MHA) caused by bone marrow carcinomatosis of breast cancer. After hemolytic anemia improved by symptomatic treatment, docetaxel therapy was started carefully. Docetaxel therapy continued effectively for 10 times without recurrence of MHA or DIC on an ambulant basis. Finally she died of liver failure due to liver metastasis 45 months after the operation. In general bone marrow carcinomatosis is often associated with DIC and rapidly progresses to its termination, however, this patient could survive for a long time maintaining good QOL by effective systemic chemotherapy.
Journal
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- Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)
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Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) 66 (5), 1023-1026, 2005
Japan Surgical Association
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Keywords
Details 詳細情報について
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- CRID
- 1390282679826950656
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- NII Article ID
- 10016685633
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- NII Book ID
- AA11189709
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- ISSN
- 18825133
- 13452843
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed