The Brugada Syndrome-An Update-

• SHIMIZU Wataru

  Division of Cardiology, Department of Internal Medicine, National Cardiovascular Center, Suita

書誌事項

タイトル別名

• Brugada Syndrome An Update

抄録

Brugada syndrome is characterized by ST-segment elevation in the right precordial leads (V₁-V₃) and an episode of ventricular fibrillation (VF) in the absence of structural heart disease. A number of reports from the world have unveiled the clinical, electrocardiographic, electrophysiologic and prognostic features of Brugada syndrome, and two recent consensus reports have suggested the diagnostic criteria of Brugada syndrome and the risk stratification for the identification of high risk Brugada patients for sudden cardiac death. SCN5A, the gene encoding the α subunit of the sodium channel, is the only gene thus far linked to Brugada syndrome; its prognostic value remains unclear. On the other hand, advances in the understanding of the cellular mechanism for Brugada phenotype derived from experimental studies have suggested possibilities for the development of strategies for managing and treating patients with Brugada syndrome. In this review, the recent understanding and knowledge of Brugada syndrome will be updated.

収録刊行物

• Internal Medicine

  Internal Medicine 44 (12), 1224-1231, 2005

  一般社団法人 日本内科学会

キーワード

• Brugada syndrome
• ST-segment
• ventricular fibrillation
• diagnosis
• prognosis
• risk stratification
• therapy

詳細情報

• CRID: 1390282679844496256
• NII論文ID: 10016917318
• NII書誌ID: AA10827774
• DOI: 10.2169/internalmedicine.44.1224
• ISSN: 13497235
• ISSN: 09182918
• NDL書誌ID: 7753917
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I7753917
• Web Site: http://www.jstage.jst.go.jp/article/internalmedicine/44/12/44_12_1224/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2006248463
• 本文言語コード: en
• データソース種別:
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