Enhancement Effects and Relaxivities of Gadolinium-DTPA at 1.5 versus 3 Tesla : A Phantom Study

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Author(s)

    • SASAKI Makoto
    • Department of Radiology, Iwate Medical University, School of Medicine
    • SHIBATA Eri
    • Department of Radiology, Iwate Medical University, School of Medicine
    • KANBARA Yoshiyuki
    • High Field Magnetic Resonance Imaging Research Institute, Iwate Medical University, School of Medicine
    • EHARA Shigeru
    • Department of Radiology, Iwate Medical University, School of Medicine

Abstract

Purpose: To investigate the difference in enhancement effects and relaxivities of the gadolinium chelate at 1.5 and 3 Tesla (T) and to elucidate the contribution of the high magnetic field to contrast enhancement in spin-echo (SE) and gradient-echo (GRE) images.<br> Methods: Phantoms containing water with or without gadopentetate dimeglumine (Gd-DTPA) at different concentrations were scanned using 1.5T and 3T MRI scanners of the same manufacturer and under the same temperature conditions and scanning parameters. Relaxivities of gadolinium, R<sub>1</sub> and R<sub>2</sub>, were estimated from serial T<sub>1</sub> and T<sub>2</sub> values of the phantoms using linear regression. Contrast enhancement ratios in SE and GRE T<sub>1</sub>-weighted images were compared at 1.5 and 3T.<br> Results: The R<sub>1</sub> and R<sub>2</sub> of Gd-DTPA at 1.5 and 3T were 4.79 and 5.14, and 4.50 and 5.09, respectively. Although the relaxivities at 3T were slightly lower than those at 1.5T, the contrast enhancement ratio improved in both SE and GRE images as a result of T<sub>1</sub> prolongation of the water at 3T.<br> Conclusion: The decrease in relaxivities of the Gd-DTPA at 3T appears to be so small that T<sub>1</sub> prolongation of the water improves contrast enhancement, suggesting a potential clinical advantage in administration of Gd-DTPA at high field strength.<br>

Journal

  • Magnetic Resonance in Medical Sciences

    Magnetic Resonance in Medical Sciences 4(3), 145-149, 2005-11-15

    Japanese Society for Magnetic Resonance in Medicine

References:  17

Cited by:  1

Codes

  • NII Article ID (NAID)
    10016941736
  • NII NACSIS-CAT ID (NCID)
    AA11648770
  • Text Lang
    ENG
  • Article Type
    Journal Article
  • ISSN
    13473182
  • Data Source
    CJP  CJPref  J-STAGE 
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