胃原発T細胞性悪性リンパ腫の1例

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  • A CASE OF PRIMARY GASTRIC T-CELL MALIGNANT LYMPHOMA

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A 71-year-old female with positive fecal occult blood test was admitted to our hospital for further examination. Gastric endoscopy revealed a type-2 ulcerative lesion on the posterior wall of lower part of her stomach. Malignant lymphoma was diagnosed by the biopsy specimen from the tumor. There were neither lymphadenopathy, splenomegaly, enlargement of liver, nor abnormal cells in the peripheral blood. Serum lactate dehydrogenase and calcium were within normal limit. Soluble interleukin-2 receptor (sIL-2R) was 1680U/ML. Human T lymphotropic virus type-1 (HTLV-1) antibody was positive. Total gastrectomy and lymphnode dissection (D2) were done. Pathological diagnosis of the resected specimen was T-cell malignant lymphoma of the stomach. Although sIL-2R level dropped to the normal limit for a while, it increased again two years after the operation. Lymphnode swelling appeared in the paraaortic area and pelvic cavity and also in the thigh. Her clinical conditions progressively worsened during period of a month. She died from infection caused by recurrent malignant lymphoma, 30 months after the operation.

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