The Test Meal A: A Pilot Model for the International Standard of Test Meal for an Assessment of Both Postprandial Hyperglycemia and Hyperlipidemia

DOI Web Site 5 Citations 25 References
  • Yoshino Gen
    Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Toho University School of Medicine
  • Tominaga Makoto
    Department of Laboratory Medicine, Yamagata University School of Medicine
  • Hirano Tsutomu
    First Department of Internal Medicine, Showa University School of Medicine
  • Shiba Teruo
    Department of Internal Medicine, Mitsui Memorial Hospital
  • Kashiwagi Atsunori
    The Third Department of Medicine, Shiga University of Medical Science
  • Tanaka Akira
    Department of Health and Nutrition, College of Human and Environmental Studies, Kanto-gakuin University
  • Tada Norio
    Division of General Medicine, Kashiwa Hospital, Department of Internal Medicine, The Jikei University School of Medicine
  • Onuma Tomio
    Internal Medicine, Diabetes and Endocrinology, Juntendo Geriatric Medical Center, Juntendo University School of Medicine
  • Egusa Genshi
    Egusa Genshi Clinic
  • Kuwashima Masamichi
    Department of Clinical Biology and Medicine, Institute of Health Bioscience, The University of Tokushima Graduate School
  • Sanke Tokio
    Department of Clinical Laboratory Medicine, Wakayama Medical University
  • Oikawa Shinnichi
    Division of Endocrinology and Metabolism, The Third Department of Medicine, Nippon Medical School
  • Honda Keiko
    Department of Applied Nutrition (Medicine Nutrition) Undergraduate School of Nutrition Sciences, Kagawa Nutrition University
  • Tachikawa Tomoko
    Kagoshima Prefecture Dietetic Association

Bibliographic Information

Other Title
  • 食後高血糖と食後高脂血症を同時に観察するテストミールのパイロットモデルの開発
  • 委員会報告 食後高血糖と食後高脂血症を同時に観察するテストミールのパイロットモデルの開発--テストミールAについての報告
  • イインカイ ホウコク ショク ゴ コウケットウ ト ショク ゴ コウシケツショウ オ ドウジ ニ カンサツ スル テストミール ノ パイロット モデル ノ カイハツ テストミール A ニ ツイテ ノ ホウコク
  • —テストミールAについての報告—

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Abstract

Not only postprandial hyperglycemia, but also postprandial hyperlipidemia contributes to the development of atherosclerosis. International standards for test meals used to assess both postprandial hyperglycemia and hyperlipidemia simultaneously must now be established. In this report, we prepared a “test meal A” containing a total energy of 450 kcal with 51.4% from carbohydrates, 33.3% from fats and 15.3% from proteins. Eighteen diabetics, 12 IGTs and 29 subjects with normal glucose tolerance, were enrolled in this study. An oral glucose tolerance test was performed one week after the test meal load. There was a close relationship between blood glucose values at 2 hours after glucose loading and at 2 hours after test meal loading. The blood glucose value of 200 mg/dl at 2 hours after glucose loading corresponded to 150 mg/dl at the same sampling point after test meal loading, and the blood glucose value of 140 mg/dl at 2 hours after glucose loading corresponded to 110 mg/dl at the same sampling point after test meal loading. A significant elevation in plasma triglyceride was found in normotriglyceridemic subjects after the test meal load. Thus, the “test meal A”, which we demonstrated here, could be used as a pilot model for the assessment of both postprandial hyperglycemia and hyperlipidemia simultaneously in diabetic subjects.

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