テクスチャー解析法を用いた転写開始部位周辺配列からのパターン抽出 Pattern Extraction from a Sequence Surrounding a Transcriptional Starting Site Using Texture Analysis : The Utility of Texture Analysis Based on the Gray Level Run Length Matrix

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Author(s)

    • 村瀬 治比古 MURASE Haruhiko
    • 大阪府立大学大学院農学生命科学研究科 Laboratory of Phytotronics and Sensibility Engineering, Graduate School of Agriculture and Biological Sciences, Osaka Prefecture University
    • 福井 一広 FUKUI Kazuhiro
    • 大阪府立大学大学院農学生命科学研究科 Laboratory of Phytotronics and Sensibility Engineering, Graduate School of Agriculture and Biological Sciences, Osaka Prefecture University

Abstract

遺伝子のコード領域や転写制御配列の特異的配列を特定するために隠れマルコフモデルなどの計算手法が開発され適用されている.しかし, 転写制御領域の塩基配列と遺伝子発現の関係については多くの異なった見解がある.そこで, 転写開始部位の周辺配列について何らかの物理的な特徴の存在を期待してテクスチャー解析を適用し, テクスチャ特徴量を抽出した.ランレングス行列によるテクスチャー解析を用い, 熱ショック蛋白質の転写制御領域に適用した.そして特徴量の変化を一つのパターンと捉えて, 転写開始部位の周辺配列を表すことにした.

The computational methods to detect the coding regions of genes and specific sequences of the transcriptional control region using stochastic models such as the hidden Markov Model have been developed. But there are still aspects of the control of the gene expression based on a sequence of the transcriptional control region that have not been described. We report here our attempt to apply texture analysis to a sequence surrounding a transcriptional starting site to extract the features. We developed the features extraction program by employing texture analysis based on the gray level run length matrix and applied it to sequences surrounding transcriptional starting sites of genes coding the heat shock proteins. Thus we could successfully represent features extracted from a sequence surrounding transcriptional starting sites as specific patterns of them.

Journal

  • Environment Control in Biology

    Environment Control in Biology 42(3), 169-176, 2004-09-30

    Japanese Society of Agricultural, Biological and Environmental Engineers and Scientists

References:  7

Codes

  • NII Article ID (NAID)
    10018078956
  • NII NACSIS-CAT ID (NCID)
    AN00129558
  • Text Lang
    ENG
  • Article Type
    ART
  • ISSN
    05824087
  • NDL Article ID
    7105928
  • NDL Source Classification
    ZR1(科学技術--生物学)
  • NDL Call No.
    Z18-52
  • Data Source
    CJP  NDL  J-STAGE  JASI 
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