Development of a Knee-Loading Joint Supporter for Potential Use in Preventing Bone Loss during Spaceflight/Aging

DOI Web Site 36 References
  • Su Min
    Department of Biomedical Engineering, Indiana University Purdue University Indianapolis, Indianapolis, IN, USA
  • Zhang Ping
    Department of Anatomy & Cell Biology, Indiana University Purdue University Indianapolis, Indianapolis, IN, USA
  • Yokota Hiroki
    Department of Biomedical Engineering, Indiana University Purdue University Indianapolis, Indianapolis, IN, USA Department of Anatomy & Cell Biology, Indiana University Purdue University Indianapolis, Indianapolis, IN, USA
  • M. Malacinski George
    Department of Biology, Indiana University, Bloomington, IN, USA

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Abstract

As a countermeasure for bone loss experienced by astronauts during the microgravity of spaceflight, and by aging patients (e.g., osteoporosis), the designs of devices for the application of lateral loads to the knee joint are described. These "knee-loading joint supporters (KJS)" are intended to clamp onto the human knee and provide variable, intermittent pulses of mechanical load. Based on previous experimentation with mouse models, it is expected that these KJS devices will facilitate human bone strengthening.

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