Quantification of Left Ventricular Volumes from Cardiac Cine MRI Using Active Contour Model Combined with Gradient Vector Flow

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  • TANKI Nobuyoshi
    Department of Medical Physics and Engineering, Division of Medical Technology and Science, Course of Health Science, Graduate School of Medicine, Osaka University
  • MURASE Kenya
    Department of Medical Physics and Engineering, Division of Medical Technology and Science, Course of Health Science, Graduate School of Medicine, Osaka University
  • KUMASHIRO Masayuki
    Department of Medical Physics and Engineering, Division of Medical Technology and Science, Course of Health Science, Graduate School of Medicine, Osaka University Department of Radiology, Kurashiki Central Hospital
  • MOMOI Risa
    Department of Medical Physics and Engineering, Division of Medical Technology and Science, Course of Health Science, Graduate School of Medicine, Osaka University
  • YANG Xiaomei
    Department of Medical Physics and Engineering, Division of Medical Technology and Science, Course of Health Science, Graduate School of Medicine, Osaka University
  • TABUCHI Takashi
    Department of Radiology, Kurashiki Central Hospital
  • NAGAYAMA Masako
    Department of Radiology, Kurashiki Central Hospital
  • WATANABE Yuji
    Department of Radiology, Kurashiki Central Hospital

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Abstract

We investigated the feasibility of combining the active contour model with gradient vector flow (Snakes-GVF) to estimate left ventricular (LV) volumes from cardiac cine magnetic resonance imaging (MRI). MRI data were acquired from 27 patients, including 14 adults (9 men, 5 women, 55.0±23.3 years) and 13 children (10 boys, 3 girls, 2.7±2.1 years) using Gyroscan Intera (1.5 Tesla, Philips Medical Systems). LV volumes were calculated by adding the areas surrounded by the contour extracted by Snakes-GVF and compared with volumes estimated by manual tracing. Those estimated by Snakes-GVF [y (mL)] correlated well with those estimated by manual tracing [x (mL)]. In adult cases, the regression equation and correlation coefficient were y=1.008x-0.517 and 0.996, respectively. In pediatric cases, they were y=1.174x-2.542 and 0.992, respectively. In conclusion, Snakes-GVF is a powerful and useful tool for quantifying LV volumes using cardiac MRI.<br>

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