Study of Solidified Enteral and Oral Nutritional Formula on Transformation and Transit in Digestive Tract-Fundamental Experiments in Rats-

• TASHIRO Katsufumi

  Technical Research Laboratories, EN Otsuka Pharmaceutical Co., Ltd.

• HIGASHIGUCHI Takashi

  Department of Surgery & Palliative Care, Fujita Health University School of Medicine

• TAKEDA Yuko

  Technical Research Laboratories, EN Otsuka Pharmaceutical Co., Ltd.

• TOMITSUKA Toshie

  Technical Research Laboratories, EN Otsuka Pharmaceutical Co., Ltd.

• FUJISE Nobuaki

  Technical Research Laboratories, EN Otsuka Pharmaceutical Co., Ltd.

• NAKAMURA Tsuyoshi

  Technical Research Laboratories, EN Otsuka Pharmaceutical Co., Ltd.

• MASUNAGA Hiroaki

  Technical Research Laboratories, EN Otsuka Pharmaceutical Co., Ltd.

• ITO Akihiro

  Department of Surgery & Palliative Care, Fujita Health University School of Medicine

Bibliographic Information

Other Title

• 固形化栄養剤の消化管内形状変化と移行に関する研究－ラットを用いた基礎的検討－

Abstract

Enteral nutrition, which was solidified by pectin, was studied in rats. Namely, solidified enteral nutrition dissolution in simulated digestive fluids, transit effects, the occurrence of gastroesophageal reflux and fecal status were monitored.<BR>In comparison with nutrition solidified by agar or gelatin, the nutrition solidified by pectin maintained its solidity in simulated gastric juices, but quickly dissolved in simulated intestinal juices. In comparison with liquid forms of nutrition, solidified nutrition exhibited prolonged gastric emptying time, while no difference in intestinal transit was observed. Solidified nutrition significantly reduced the occurrence of gastroesophageal reflux and the incidence of diarrhea in rats.

Journal

• Jomyaku Keicho Eiyo

  Jomyaku Keicho Eiyo 21 (2), 2_115-2_125, 2006

  Japanese Society for Parenteral and Enteral Nutrition

Keywords

• 固形化栄養剤
• 胃食道逆流
• ラット

Details

• CRID: 1390001204425309440
• NII Article ID: 130004487080
• NII Article ID: 10018164595
• NII Book ID: AA11574426
• DOI: 10.11244/jjspen.21.2_115
• ISSN: 18813623
• ISSN: 13444980
• Web Site: https://search.jamas.or.jp/link/ui/2006315190
• Text Lang: ja
• Data Source:
  • JaLC
  • CiNii Articles
• Abstract License Flag: Disallowed