十二指腸ポリープに粘液貯留を伴う偽浸潤を認め,診断に苦慮した不全型Peutz‐Jeghers症候群の1例

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  • INCOMPLETE PEUTZ-JEGHERS SYNDROME WITH PSEUDOINVASION OF DUODENAL POLYP: REPORT OF A CASE

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A 37-year-old man was admitted to our hospital for the further examination and therapy of the duodenal tumor. Gastrointestinal endoscopy revealed a large polypoid lesion which had a rough, nodular surface in the duodenal bulb. And at the side of tumor edge, there were elevated lesions like a submucosal tumor. Endoscopic ultrasonography showed a slight hypere-choic mass derived from second to third layers of the duodenal wall. Cystic areas were contained within the tumor. Fine-needle aspiration biopsy was performed. The biopsy speci-men showed epithelial and Brunner's gland cells hyperplasia. Surgical resection was performed in consideration of the tumor size, and duodenal polypoid lesion measured 50× 43× 28mm in size. The tumor was diagnosed histologically as Peutz Jeghers (P-J) polyp with pseudoinvasion in the submucosa to subserosa. Additionally, another hamartomatous polyps were observed in the jejunum and ileum. Neither family history of intestinal polyposis nor muco-cutaneous pigmentation was observed, the case was diagnosed as incomplete Peutz-Jeghers Syndrome.

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