テリスロマイシンが有効であったレジオネラ肺炎の3例

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書誌事項

タイトル別名
  • Successful Telithromycin Therapy of <I>Legionella</I> Pneumonia
  • 症例 テリスロマイシンが有効であったレジオネラ肺炎の3例
  • ショウレイ テリスロマイシン ガ ユウコウ デ アッタ レジオネラ ハイエン ノ 3レイ
  • Successful Telithromycin Therapy of Legionella Pneumonia
  • Report of Three Cases

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抄録

Legionella species have been widely recognized as among the important causative organisms of community-acquired pneumonia in Japan. A delay in the start of adequate treatment has a negative influence on the outcome of the disease. Telithromycin, the first oral ketolide antibacterial, was developed for the treatment of community-acquired pneumonia, including Legionella pneumonia. However, few reports have indicated the efficacy of telithromycin in community-acquired pneumonia caused by Legionella species. We report three cases of Legionella pneumonia, that were improved by early telithromycin therapy. The first patient (67-year-old man) had bronchiectasis as an underlying disease, and the second patient (73-year-old man) had diabetes mellitus and chronic renal failure. The third patient (62-year-old man) developed pneumonia after a spa tour. The diagnosis of Legionella pneumonia was made on the basis of the presence of a single IgG titer of 1/256 in case 1 and positive antigenuria in cases 2 and 3. The patients were classified into a mild group (case 1) and a moderate group (cases 2 and 3) based on the severity of the community-acquired pneumonia according to the 2005 Japanese Respiratory Society Guidelines. The results support the efficacy of telithromycin in mild to moderate Legionella pneumonia.

収録刊行物

  • 感染症学雑誌

    感染症学雑誌 80 (4), 418-422, 2006

    一般社団法人 日本感染症学会

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