G群に凝集する<I>Streptococcus dysgalactiae</I> subsp. <I>equisimilis</I>による劇症型溶血レンサ球菌感染症の1例

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タイトル別名
  • A Case of Severe Necrotizing Cellulitis Caused by Group G <I>Streptococcus dysgalactiae</I> subsp. <I>equisimilis</I>
  • 症例 G群に凝集するStreptococcus dysgalactiae subsp. equisimilisによる劇症型溶血レンサ球菌感染症の1例
  • ショウレイ Gグン ニ ギョウシュウ スル Streptococcus dysgalactiae subsp equisimilis ニ ヨル ゲキショウガタ ヨウケツ レンサ キュウキン カンセンショウ ノ 1レイ
  • A Case of Severe Necrotizing Cellulitis Caused by Group G Streptococcus dysgalactiae subsp. equisimilis

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Group G streptococcus (GGS) is infrequently associated with severe invasive soft tissue infection and toxic shock syndrome. A 74-year-old woman with a history of lymphedema of the lower extremities after surgical and radiation therapy for uterine cancer and diabetic mellitus and admitted for swelling of the right leg, fever, and dyspnea. She presented with shock and necrotizing cellulitis of the right lower extremity. Laboratory tests showed leukocytepenia, acute renal and liver dysfunction, and muscle damage. She rapidly developed multiple organ failure and necrotizing cellulitis. A swab from skin vesicle, throat, and blood culture grew Group G Streptococcus dysgalactiae subsp. equisimilis. Despite endotoxin hemoadsorption therapy, administration of antibiotics, and intravenous immunoglobulin, she died 9 days after admission due to toxic shock syndrome caused by GGS. The M-protein gene (emm) typing of GGS isolated from both blood and skin lesion showed stG 485.0. Three virulence genes, sagA, slo and skcg, were detected from GGS isolated from them.

収録刊行物

  • 感染症学雑誌

    感染症学雑誌 80 (4), 436-439, 2006

    一般社団法人 日本感染症学会

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