小児気管支喘息における肺炎マイコプラズマ特異ＩｇＭ抗体陽性率

• 白井 潤二

  日本医科大学付属多摩永山病院小児科

• 高瀬 真人

  日本医科大学付属多摩永山病院小児科

• 今井 丈英

  日本医科大学付属多摩永山病院小児科

• 飛田 正俊

  日本医科大学付属多摩永山病院小児科

書誌事項

タイトル別名

• Prevalence of <I>Mycoplasma Pneumoniae</I> Specific IgM Antibody in Childhood Asthma

抄録

“ImmunoCard Mycoplasma^®” (IC-MP) qualitatively detects Mycoplasma Pneumoniae (MP) specific IgM antibody, and is widely accepted as a rapid diagnostics for acute MP infection. We used the kit to examine the relationship between MP infection and acute exacerbation of asthma in children.Of 80 children (0-14y/o) hospitalized for severe asthma, IC-MP was positive in 63.8%; while 70.7% in the control group of 133 allergic children with stable asthma, atopic dermatitis and/or food allergy was proven positive.Most of IC-MP positive serum samples were shown to have low values of particle agglutination (PA) antibodies, and repeated IC-MP tests were persistently positive for more than one year.Thus, positive IC-MP in a single sample only indicates past history of MP infection. In order to examine the role of MP infection in acute exacerbation of asthma, either the proof of MP existence in the respiratory tract or significant rise of MP specific antibodies in paired sera should be investigated.<BR>However, in the younger age group (1-3y/o), contrary to our expectations, significantly higher positive rate of IC-MP was observed in the control group (76.8%), compared with acute asthma group (48.9%: p=0.003).Further investigation is necessary to find out the explanations for this intriguing data.

収録刊行物

• 日本小児呼吸器疾患学会雑誌

  日本小児呼吸器疾患学会雑誌 17 (1), 11-17, 2006

  日本小児呼吸器疾患学会

キーワード

• 小児
• マイコプラズマ
• 気管支喘息
• 増悪因子

詳細情報

• CRID: 1390282679396776064
• NII論文ID: 10018262546
• NII書誌ID: AN10297832
• DOI: 10.5701/jjpp.17.11
• ISSN: 21853754
• ISSN: 09183876
• Web Site: https://search.jamas.or.jp/link/ui/2006258612
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可