A case of gastric endocrine cell carcinoma with liver metastasis showing rapid growth during pregnancy and marked reduction by systemic chemotherapy after delivery

  • SHIRADO Akemi
    Department of Internal Medicine II, Faculty of Medicine, University of Miyazaki
  • UTO Hirofumi
    Department of Internal Medicine II, Faculty of Medicine, University of Miyazaki
  • KUSUMOTO Kazunori
    Department of Internal Medicine II, Faculty of Medicine, University of Miyazaki
  • KUROGI Joji
    Department of Internal Medicine II, Faculty of Medicine, University of Miyazaki
  • SAKAMOTO Hidemori
    Department of Internal Medicine II, Faculty of Medicine, University of Miyazaki
  • HASUIKE Satoru
    Department of Internal Medicine II, Faculty of Medicine, University of Miyazaki
  • NAGATA Kenji
    Department of Internal Medicine II, Faculty of Medicine, University of Miyazaki
  • HAYASHI Katsuhiro
    Department of Internal Medicine II, Faculty of Medicine, University of Miyazaki
  • IWAMITSU Akihiro
    Department of Hepatology and Gastroenterology, Miyazaki Medical Center Hospital
  • HORI Takeshi
    Department of Hepatology and Gastroenterology, Miyazaki Medical Center Hospital
  • IBUSUKI Kazuhiko
    Department of Surgery, Koga General Hospital
  • IDO Akio
    Translational Research Center, Kyoto University Hospital
  • TSUBOUCHI Hirohito
    Translational Research Center, Kyoto University Hospital Department of Digestive and Life Style Related Disease, Kagoshima University Graduate School of Medicine and Dental Sciences

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Other Title
  • 妊娠中に肝転移巣が急速に増大し,出産後の化学療法が著効した胃内分泌細胞癌の1例

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Abstract

A 28-year-old woman was given a diagnosis of gastric endocrine cell carcinoma with multiple liver metastases in 1997. Chemotherapy was administered for treatment after a distal gastrectomy and hepatic tumor resection, and she had shown no sign of relapse after 2002.<br> In February 2004, she was in the third month of pregnancyC and experienced recurrent liver metastasis. Although the tumor grew rapidly from 3cm to 10cm during her pregnancy, its size was significantly reduced with systemic chemotherapy after delivery. This is a rare case in which a liver metastasis of a gastric endocrine cell carcinoma grew during the course of pregnancy.<br>

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