A case of pancreatic intraductal papillary-mucinous carcinoma with penetration to the stomach and splenic abscess.

  • KANEMASA Kazuyuki
    Department of Gastroenterology and Hepatology, Nara City Hospital
  • SUMIDA Yoshio
    Department of Gastroenterology and Hepatology, Nara City Hospital
  • IMAMURA Shigeyoshi
    Department of Gastroenterology and Hepatology, Nara City Hospital
  • KATOH Naho
    Department of Gastroenterology and Hepatology, Nara City Hospital
  • TACHIBANA Shunji
    Molecular Gastroenterology and Hepatology, School of Medical Science, Kyoto Prefectural University of Medicine
  • MITSUFUJI Shoji
    Molecular Gastroenterology and Hepatology, School of Medical Science, Kyoto Prefectural University of Medicine
  • KATAOKA Keisho
    Molecular Gastroenterology and Hepatology, School of Medical Science, Kyoto Prefectural University of Medicine
  • OKANOUE Takeshi
    Molecular Gastroenterology and Hepatology, School of Medical Science, Kyoto Prefectural University of Medicine

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Other Title
  • 胃および脾臓へ穿破し,脾膿瘍を合併した膵管内乳頭粘液性腺癌(IPMC)の1例

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Abstract

We report the case of an 80-year-old man given a diagnosis of pancreatic intraductal papillary-mucinous carcinoma (IPMC) and early gastric cancer. He refused surgery, therefore endoscopic mucosal resection (EMR) for gastric cancer and careful observation were performed. Penetration of the IPMC to the stomach was observed 3 months later. Ten months after the initial diagnosis, he was found to have a splenic abscess and was subsequently treated by antibiotics and percutaneous drainage, and a fistula between the IPMC and the splenic abscess was observed. We suppose IPMC penetration to the spleen and bacterial transmission from the stomach through the fistula caused the splenic abscess. While IPMC is recognized as a low-grade malignancy, some cases of invasive carcinoma with fistulation to adjacent organs have been reported. To the best of our knowledge, this is the first case of IPMC associated with splenic abscess due to pancreato-splenic fistula.<br>

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