A CASE OF OCCULT AND INFLAMMATORY BREAST CANCER DEVELOPED AFTER CHEMOTHERAPY FOR PERICARDIAL METASTASIS

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  • 癌性心胸膜炎で発症し，化学療法後に診断された潜在性，炎症性乳癌の１例

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Abstract

We report a case of occult and inflammatory breast cancer developed after chemotherapy for pericardial metastasis.<br> A 32-year-old female was admitted to the hospital because of dyspnea in July 1997. Chest X-ray and CT scan of the chest revealed effusion in the pericardial space. Subsequently, pericardiocentensis was done and pericardial fluid was aspirated. Cytological examination of the aspirated speicemen showed adenocarcinoma cells. TBLB showed no malignancy, but we suspected that she had pericarditis carcinomatosa due to metastasis of lung cancer. No abnormalities of the breasts were revealed. Local and systemic chemotherapy was started and a complete respose (CR) was achieved. However, 2 months later, she was seen at the hospital because of redness and swelling of the right breast. Fine needle aspiration biopsy showed adenocarcinoma cells, and inflammatory breast cancer was diagnosed. She underwent a right modified radical mastectomy with lymph node dissection. Clinicopathological studies confirmed that the right breast cancer was the primary origin of the pericardial metastasis. She died of bilateral lung metastasis. 1 year after the first admission.

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