Ｈｕｍｏｒａｌ　ｈｙｐｅｒｃａｌｃｅｍｉａ　ｏｆ　ｍａｌｉｇｎａｎｃｙ（ＨＨＭ）を呈した骨転移陰性の進行乳癌の１例

• 田代 英哉

  大分県立病院外科

• 増野 浩二郎

  大分県立病院外科

• 藤井 及三

  大分県立病院外科

• 坂田 久信

  大分県立病院外科

書誌事項

タイトル別名

• REPORT OF A CASE OF ADVANCED BREAST CANCER WITH NO BONE METASTASIS COMPLICATED BY HUMORAL HYPERCALCEMIA OF MALIGNANCY

抄録

A case of advanced breast cancer with no bone metastasis complicated by humoral hypercalcemia of malignancy was reported. The patient was a 46-year-old woman who complained of general fatigue, anorexia and vomiting during chemotherapy consisting of docetaxel and cyclophosphamide for liver and lung metastases from breast cancer. The laboratory data showed a remarkable incrcase in serum calcium (9.7mEq/l) and PTHrP (555pmol/l) without elevation of PTH (13pg/l). Bone scintigraphy, Xray and CT revealed no bone metastases. The lumbar vertebra bone density fell 77%-92%. Based on these findings, the diagnosis was humoral hypercalcemia of malignancy complicated by advanced breast cancer with no bone metastases.<br> Serum calcium was well controlled for a long time by antihypercalcemic therapy consisting of intravenous saline, incadronate, corticosteroid and calcitonin accompanied by chemotherapy with epirubicin.<br> Even if bone metastases are not evident in breast cancer patients, the clinician should keep in mind the possibility of humoral hypercalcemia of malignancy.

収録刊行物

• 日本臨床外科学会雑誌

  日本臨床外科学会雑誌 67 (10), 2324-2327, 2006

  日本臨床外科学会

キーワード

• 乳癌
• 高カルシウム血症
• 骨転移

詳細情報

• CRID: 1390001204846669568
• NII論文ID: 130003604745
• NII論文ID: 10018390908
• NII書誌ID: AA11189709
• DOI: 10.3919/jjsa.67.2324
• ISSN: 18825133
• ISSN: 13452843
• Web Site: http://www.jstage.jst.go.jp/article/ringe1998/67/10/67_10_2324/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2007089562
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可