A CASE OF COLON METASTASIS FROM BREAST CANCER DIAGNOSED BY LAPAROSCOPIC BIOPSY

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  • 腹腔鏡下生検が鑑別に有用であった乳癌大腸転移の1例

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Abstract

A 72-year-old woman who had been undergoing hemodialysis for renal failure due to rephrotuber-culosis underwent modified radical mastectomy for right breast cancer, which was histologically invasive lobular carcinoma in stage III (T2N2M0). Nine months after the surgery, she was seen at the hospital because of right lower abdominal pain and constipation. Imaging methods revealed a narrowing and wall thickening at the splenic flexura, indicating metastasis of breast cancer to the transverse colon. Histopathological study of endoscopic biopsies revealed no evidence of metastasis. Laparoscopy showed wall thickening in the vicinity of the splenic flexura, a mesenteric nodule, and regional lymph node swelling. We excised the nodule and lymph nodes and confirmed the diagnosis of metastatic breast cancer.<br> Colon metastasis of breast cancer commonly occures in the terminal stage of breast cancer, and is rarely recognized as the initial metastasis. To make the definitive diagnosis of metastasic breast cancer is difficult even after endoscopic biopsies. Laparoscopic biopsies would be helpful in making the diagnosis and in avoiding unnecessary surgical treatment with early initiation of chemotherapy.

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