<I>In Vitro</I>Activity of Methylrosaniline Chloride (Gentian Violet) as Disinfectant Against<I>Candida</I>spp. and<I>Trichosporon</I>spp. Isolated from Blood Samples

DOI Web Site PubMed 4 Citations 20 References
  • KONDO Shigemi
    Department of Clinical Pathology, Juntendo University School of Medicine
  • YAMADA Toshihiko
    Department of Clinical Pathology, Juntendo University School of Medicine Ichikawa City, Health Service Facility for the Aged
  • SATOH Naotake
    Department of Clinical Pathology, Juntendo University School of Medicine Department of Clinical Laboratory, Juntendo Koto Geriatric Medical Center
  • SAIONJI Katsu
    Department of Clinical Pathology, Juntendo University School of Medicine Department of Laboratory Medicine, National Defense Medical College
  • OGURI Toyoko
    Department of Clinical Laboratory, Juntendo University Hospital
  • IGARI Jun
    Department of Clinical Pathology, Juntendo University School of Medicine

Bibliographic Information

Other Title
  • 塩化メチルロザニリン (ゲンチアナ紫) の血液由来真菌 (カンジダ属, トリコスポロン属) に対する<I>in vitro</I>抗菌作用
  • 塩化メチルロザニリン(ゲンチアナ紫)の血液由来真菌(カンジダ属,トリコスポロン属)に対するin vitro抗菌作用
  • エンカ メチルロザニリン ゲンチアナ ムラサキ ノ ケツエキ ユライ シンキン カンジダゾク トリコスポロンゾク ニ タイスル in vitro コウキン サヨウ
  • In VitroActivity of Methylrosaniline Chloride (Gentian Violet) as Disinfectant AgainstCandidaspp. andTrichosporonspp. Isolated from Blood Samples

Search this article

Abstract

Objective: Methylrosaniline Chloride (MRC) is recognized as a disinfectant, but recently is rarely used in the clinic, because of its cytotoxicity when used continuously with conventional concentrations (1% MRC). We have reported the antibacterial activity of MRC with lower concentration against Methicillin-resistantStaphylococcus aureus(MRSA). In this study, we evaluated the antifungal activity of MRC with lower concentrations.<BR>Material and Methods: Antifungal activities of MRC againstCandidaspp. andTrichosporonspp. were tested. All strains tested were isolated from 106 blood or intravenous catheter samples at Juntendo University Hospital from 1995 to 2004. Minimum inhibitory concentrations against fungi were assayed by agar dilution, under both aerobic and anaerobic conditions.<BR>Results: A 0.01% or less concentration of MRC solutions showed marked antifungal activity againstCandidaspp. andTrichosporonspp. under aerobic or anaerobic conditions.<BR>Conclusion: A 0.01% or less concentration of MRC should be reevaluated for the control of fungal infection and MRSA infection control.

Journal

  • Kansenshogaku Zasshi

    Kansenshogaku Zasshi 80 (6), 651-655, 2006

    The Japanese Association for Infectious Diseases

Citations (4)*help

See more

References(20)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top