Assignments of B-Type Fragments in Post-Source Decay of Negative-Ion Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry of Neutral Lactooligosaccharides
We describe a detailed assignment strategy for B-type fragments of neutral lactooligosaccharides derived from negatively charged precursor ions in matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS). The post-source decay (PSD) ions produced by the loss of 180 u were assigned to the B-type fragments. The existing analyses of a series of lactooligosaccharides, as summarized in a previous report [T. Yamagaki, <i>et al</i>., <i>J. Am. Soc. Mass Spectrom</i>., <b>17</b>, 67 (2006)], assisted us in the correct assignments. A clarification of B-type fragment assignments was essential, since we considered that the generation of B-type fragments from negatively charged precursor ions was typical of MALDI PSD, as opposed to the products of electrospray ionization MS low-energy collision induced dissociation.
- 質量分析 = Mass spectroscopy
質量分析 = Mass spectroscopy 54(6), 251-254, 2006-12-01
The Mass Spectrometry Society of Japan