Simultaneous Analysis of Reactivity of L-Cysteic Acid or L-Cysteine Having Three Different Kinds of Functional Groups

• IMAIZUMI Hiroshi

  Department of Chemistry and Chemical Engineering, Faculty of Engineering, Niigata University

• NAGASAWA Satoshi

  Graduate School of Science and Technology, Niigata University

• KANO Naoki

  Department of Chemistry and Chemical Engineering, Faculty of Engineering, Niigata University

Bibliographic Information

Other Title

• 異なる３種の官能基を持つＬ‐システイン酸とＬ‐システインの反応性の同時解析
• コトナル 3シュ ノ カンノウキ オ モツ L システインサン ト L システイン ノ ハンノウセイ ノ ドウジ カイセキ

Abstract

In order to clarify both the effect of tritium (³H or T) on the ecosystem and the reactivity of materials having H atoms, the reactivity of L-cysteic acid (or L-cysteine) having three different kinds of functional groups was studied. The hydrogen-isotope exchange reaction between each compound and HTO vapor (T-for-H exchange reaction) was observed at 50-70°C, and the reaction was analyzed with both the A″-McKay plot method and the data obtained from the exchange reaction. The following seven matters have been consequently found in the T-for-H exchange reaction. (1) The reactivity of the functional groups in each compound increases with increasing temperature. (2) As to L-cysteic acid, the reactivity of SO₃H group is 2.6 times greater than that of COOH one, and is 5.6 times greater than that of NH₂ one. (3) As to L-cysteine, the reactivity of SH group is 1.4 times greater than that of COOH one, and 3.5 times greater than that of NH₂ one. (4) The reactivity of NH₂ group progressed by the substituent having large electron-attractive effect, however, the reactivity of COOH group does not so progress by such a substituent. (5) Applying the A″-McKay plot method, the reactivity of the three functional groups in each aliphatic compound can be nondestructively and simultaneously clarified under the condition of non-masking reagent. (6) Degree of T-incorporation in a certain material can be nondestructively and quantitatively clarified. (7) The results obtained in this work is useful to prevent T contamination in the environment and to clarify the reactivity of the materials having plural functional groups, and the method used in this work can be also useful as a analytical method to obtain the reactivity of multi-functional groups in a certain compound.

Journal

• RADIOISOTOPES

  RADIOISOTOPES 55 (12), 709-718, 2006

  Japan Radioisotope Association

Keywords

• simultaneous analysis of reactivity
• gas-solid reaction
• L-cysteic acid
• L-cysteine
• functional group
• <I>A″</I>-McKay plot

Details

• CRID: 1390001204156111488
• NII Article ID: 10018449099
• NII Book ID: AN00351589
• DOI: 10.3769/radioisotopes.55.709
• COI: 1:CAS:528:DC%2BD2sXhsFajsrc%3D
• ISSN: 18844111
• ISSN: 00338303
• ISSN: http://id.crossref.org/issn/00338303
• HANDLE: 10191/7107
• NDL BIB ID: 8587525
• Web Site: https://niigata-u.repo.nii.ac.jp/records/2570
• Web Site: http://id.ndl.go.jp/bib/8587525
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I8587525
• Web Site: http://www.jstage.jst.go.jp/article/radioisotopes1952/55/12/55_12_709/_pdf
• Text Lang: ja
• Data Source:
  • JaLC
  • IRDB
  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed