位相改良による電子密度図のリファイン Phase Improvement and Density Modification
Before starting model building, the first set of protein phase, which is obtained with the isomorphous replacement method, the multiple wavelength anomalous dispersion method, and/or the molecular replacement method, should be improved by the phase improvement and density modification techniques. An insufficient quality of the electron density map might be a snag for model building. Methods of phase improvement and density modification techniques must usually be performed.
日本結晶学会誌 48(6), 381-386, 2006-12-25
The Crystallographic Society of Japan