Diffuse large B-cell lymphomaの再発時に合併し，rituximab治療が奏効した赤芽球癆

DOI Web Site PubMed 被引用文献1件 参考文献6件

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タイトル別名
  • Pure red cell aplasia successfully treated with rituximab in a patient with relapsed diffuse large B-cell lymphoma
  • Diffuse large B cell lymphoma ノ サイハツジ ニ ガッペイ シ rituximab チリョウ ガ ソウコウ シタ セキガキュウロウ

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抄録

Malignant lymphoma is often accompanied by an autoimmune disorder. Here, we describe a 82-year-old woman with pure red cell aplasia (PRCA) complicated with relapsed diffuse large B-cell lymphoma. Primary treatment involving chemotherapy, continuous oral administration of prednisolone and a single infusion of rituximab was unsuccessful for both diseases, but the following treatments with 3 courses of rituximab alone for once a week dramatically improved the PRCA as well as the lymphoma. As PRCA complicated with lymphoma is rare, the ideal therapeutic strategy has not yet been established for it. Rituximab may be a good alternative for treating such cases.

収録刊行物

  • 臨床血液

    臨床血液 48 (1), 67-70, 2007

    一般社団法人 日本血液学会

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