Chemical Intertransformations of Diverse Bisdesmosidic Furostanol Saponins

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  • Zhao Dong-Mei
    Key Lab of New Drugs Design and Discovery of Liaoning Province, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University
  • Liu Yang
    Key Lab of New Drugs Design and Discovery of Liaoning Province, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University
  • Liu Yong-Xiang
    Key Lab of New Drugs Design and Discovery of Liaoning Province, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University
  • Zheng Li-Gang
    Key Lab of New Drugs Design and Discovery of Liaoning Province, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University
  • Yan Mao-Cai
    Key Lab of New Drugs Design and Discovery of Liaoning Province, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University
  • Cheng Mao-Sheng
    Key Lab of New Drugs Design and Discovery of Liaoning Province, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University

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An effective synthetic route towards four types of bisdesmosidic furostanol saponin was developed and 36 derivatives were designed and synthesized for antitumor investigation. The chemical intertransformations of these furostanol structures were discussed with respect to the E ring.

収録刊行物

  • Chemistry Letters

    Chemistry Letters 36 (2), 214-215, 2007

    公益社団法人 日本化学会

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