Evidence for the existence of soybean resistant protein that captures bile acid and stimulates its fecal excretion

DOI Web Site Web Site 被引用文献17件 参考文献28件
  • HIGAKI Noriko
    Department of Biological Resource Chemistry, Kyoto Prefectural University
  • SATO Kenji
    Department of Food Sciences and Nutritional Health, Kyoto Prefectural University
  • SUDA Hitoshi
    Department of Biological Resource Chemistry, Kyoto Prefectural University
  • SUZUKA Tomohiko
    Department of Biological Resource Chemistry, Kyoto Prefectural University
  • KOMORI Takeo
    Department of Biological Resource Chemistry, Kyoto Prefectural University
  • SAEKI Tohru
    Department of Biological Resource Chemistry, Kyoto Prefectural University
  • NAKAMURA Yasushi
    Department of Food Sciences and Nutritional Health, Kyoto Prefectural University
  • OHTSUKI Kozo
    Department of Food Sciences and Nutritional Health, Kyoto Prefectural University
  • IWAMI Kimikazu
    Department of Biological Resource Chemistry, Kyoto Prefectural University
  • KANAMOTO Ryuhei
    Department of Biological Resource Chemistry, Kyoto Prefectural University

書誌事項

タイトル別名
  • Evidence for the Existence of a Soybean Resistant Protein That Captures Bile Acid and Stimulates Its Fecal Excretion

この論文をさがす

抄録

Feeding HMF, an insoluble “high-molecular-weight fraction” from an industrial enzymatic digest of a soy protein isolate, increased the fecal excretion of bile acid concomitant with increased fecal nitrogen. An amino acid analysis revealed that this increased fecal nitrogen could be explained by an increase in the insoluble protein fraction. This suggests the existence of an indigestable protein or peptide that can be called a “resistant protein” in the feces. The presumed resistant protein was rich in hydrophobic amino acids and bound bile acid by hydrophobic interaction. The residual fraction of HMF obtained after in vitro pepsin and pancreatin digestion, showed higher in vitro bile acid-binding capacity and excreted more bile acid in vivo than HMF. Its amino acid composition was similar to that of the feces of rat fed with HMF. These results suggest that the fecal resistant protein with bile acid-binding ability could be derived from the indigestable fraction of HMF.

収録刊行物

被引用文献 (17)*注記

もっと見る

参考文献 (28)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ