Enhancement of Stress Tolerance in Saccharomyces cerevisiae by Overexpression of Ubiquitin Ligase Rsp5 and Ubiquitin-Conjugating Enzymes

• HIRAISHI Hiroyuki

  Bio-Oriented Technology Research Advancement Institution (BRAIN)

• MOCHIZUKI Mai

  Department of Bioscience, Fukui Prefectural University

• TAKAGI Hiroshi

  Department of Bioscience, Fukui Prefectural University

Bibliographic Information

Other Title

• Enhancement of Stress Tolerance in<i>Saccharomyces cerevisiae</i>by Overexpression of Ubiquitin Ligase Rsp5 and Ubiquitin-Conjugating Enzymes

Abstract

Yeast Saccharomyces cerevisiae cells overexpressing essential ubiquitin ligase Rsp5 or ubiquitin-conjugating enzymes (Ubc1-Ubc13) showed tolerance to various stresses. Co-overexpression of Rsp5 and Ubc1, Ubc2, Ubc3, Ubc5, Ubc6, Ubc9, Ubc10, Ubc11, Ubc12, or Ubc13 further enhanced stress tolerance. These results suggest that overexpression of ubiquitin-related enzymes might be a useful method for breeding novel stress-resistant strains.

Journal

• Bioscience, Biotechnology, and Biochemistry

  Bioscience, Biotechnology, and Biochemistry 70 (11), 2762-2765, 2006

  Japan Society for Bioscience, Biotechnology, and Agrochemistry

Keywords

• Rsp5 ubiquitin ligase
• ubiquitin-conjugating enzyme
• stress tolerance
• <I>Saccharomyces cerevisiae</I>

Details

• CRID: 1390282681454261888
• NII Article ID: 10018525103
• NII Book ID: AA10824164
• DOI: 10.1271/bbb.60250
• COI: 1:CAS:528:DC%2BD28XhtlSit7vK
• ISSN: 13476947
• ISSN: 09168451
• NDL BIB ID: 8560783
• PubMed: 17090950
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I8560783
• Web Site: http://www.tandfonline.com/doi/pdf/10.1271/bbb.60250
• Text Lang: en
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
• Abstract License Flag: Disallowed