血液透析患者における冠動脈石灰化とＣａ代謝および血中アディポネクチンとの検討

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  • Relationship between the coronary artery calcification and calcium metabolism and plasma adiponectin level in patients with hemodialysis
  • ケツエキ トウセキ カンジャ ニ オケル カンドウミャク セッカイカ ト Ca タイシャ オヨビ ケッチュウ アディポネクチン ト ノ ケントウ

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It has been reported that the plasma adiponectin (ADPN) level was reduced in patients with coronary artery diseases. To investigate the relationship between coronary artery calcification and plasma ADPN, calcium metabolism patients in with hemodialysis (HD), we measured the Agaston score, as a indicator of coronary artery calcification, using multi-slice CT, calcium (Ca)×phosphate (P) product and parathyroid hormone (intact-PTH) in 32 patients with chronic hemodialysis. The Agaston score was related positively to the Ca×P product, intact-PTH and duration of HD, but inversely to plasma ADPN. These findings suggest the possibility that a low plasma ADPN level, as well as the abnormal calcium metabolism, is a risk factor for coronary artery calcification.

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