The Safe Limits of Mechanical Factors in the Apnea Testing for the Diagnosis of Brain Death
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- Olguner Çimen
- Department of Anesthesiology and Reanimation, Dokuz Eylül University, School of Medicine
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- Koca Ugur
- Department of Anesthesiology and Reanimation, Dokuz Eylül University, School of Medicine
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- Akan Mert
- Department of Anesthesiology and Reanimation, Dokuz Eylül University, School of Medicine
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- Karci Ayse
- Department of Anesthesiology and Reanimation, Dokuz Eylül University, School of Medicine
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- Elar Zahide
- Department of Anesthesiology and Reanimation, Dokuz Eylül University, School of Medicine
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抄録
Apneic oxygenation is an apnea testing method in the diagnosis of brain death. In this method, oxygen (O2) is delivered into the trachea via an O2 catheter (O2C). However, barotrauma may develop during O2 insufflation into the trachea. Oxygen catheter diameters, O2 catheter tip position in the trachea, and O2 flow rate have been proposed as causes of barotrauma. This study was designed to highlight the airway pressure changes during apneic oxygenation in a model consisting of an anesthesia bag, which was connected to a pressure transducer and to an endotracheal tube (ETT). The pressure of the system was monitored while delivering O2 continuously to the system through O2C of different diameters, which were placed in the ETT. Tested variables were ETT/O2C ratio, O2C tip position in ETT (proximal 1/3 of the ETT, mid point of the ETT, and distal 1/3 of the ETT) and O2 flow rate (6, 8, and 10 L min−1). The increase in the airway pressure significantly correlated with O2</sup>C tip position in ETT (p = 0.017). ETT/O2C ratio smaller than 1.75 caused significantly high airway pressures (p < 0.05). The pressure was significantly higher at the flow rate of 10 L min−1 O2 compared with the flow rate of 6 L min−1 O2 (p < 0.01). Thus, ETT/O2C ratio, O2C tip position in ETT and O2 flow rate are the important factors that determine the airway pressure in the trachea during O2</sup> insufflation. In conclusion, overlooked mechanical factors dangerously increase airway pressure during apnea testing.
収録刊行物
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- The Tohoku Journal of Experimental Medicine
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The Tohoku Journal of Experimental Medicine 211 (2), 115-120, 2007
東北ジャーナル刊行会
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詳細情報 詳細情報について
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- CRID
- 1390282679217803136
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- NII論文ID
- 130004459539
- 10018730969
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- NII書誌ID
- AA00863920
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- ISSN
- 13493329
- 00408727
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可