Study of the characteristics of gastroesophageal reflux disease (NERD, in particular) as discovered in a mass survey.

• KOBAYASHI Takashi

  Department of Internal Medicine Second Teaching Hospital Fujita Health University School of Medicine

• YOSHINO Junji

  Department of Internal Medicine Second Teaching Hospital Fujita Health University School of Medicine

• WAKABAYASHI Takao

  Department of Internal Medicine Second Teaching Hospital Fujita Health University School of Medicine

• INUI Kazuo

  Department of Internal Medicine Second Teaching Hospital Fujita Health University School of Medicine

• OKUSHIMA Kazumu

  Department of Internal Medicine Second Teaching Hospital Fujita Health University School of Medicine

• MIYOSHI Hironao

  Department of Internal Medicine Second Teaching Hospital Fujita Health University School of Medicine

• NAKAMURA Yuta

  Department of Internal Medicine Second Teaching Hospital Fujita Health University School of Medicine

• KAMIYA Naoki

  Department of Internal Medicine Second Teaching Hospital Fujita Health University School of Medicine

• NAITOH Takehito

  Department of Internal Medicine Second Teaching Hospital Fujita Health University School of Medicine

• KIMURA Yukio

  Department of Internal Medicine Second Teaching Hospital Fujita Health University School of Medicine

• NOMURA Yukinobu

  Department of Internal Medicine Second Teaching Hospital Fujita Health University School of Medicine

• HATTORI Nobuyuki

  Department of Internal Medicine Second Teaching Hospital Fujita Health University School of Medicine

• CHIKAISHI Toshihiko

  Department of Internal Medicine Second Teaching Hospital Fujita Health University School of Medicine

• HATTORI Masashi

  Department of Internal Medicine Second Teaching Hospital Fujita Health University School of Medicine

• KAMATA Michiko

  Department of Internal Medicine Second Teaching Hospital Fujita Health University School of Medicine

• KOSAKA Toshihito

  Department of Internal Medicine Second Teaching Hospital Fujita Health University School of Medicine

• NAKAI Yoshitaka

  Department of Internal Medicine Second Teaching Hospital Fujita Health University School of Medicine

• SHIOTA Kunihito

  Department of Internal Medicine Second Teaching Hospital Fujita Health University School of Medicine

• MISAWA Daisuke

  Department of Internal Medicine Second Teaching Hospital Fujita Health University School of Medicine

• TOMOMATSU Yuichiro

  Department of Internal Medicine Second Teaching Hospital Fujita Health University School of Medicine

• FUJIMOTO Masao

  Department of Internal Medicine Second Teaching Hospital Fujita Health University School of Medicine

• SUGIYAMA Kazuhisa

  Department of Internal Medicine Second Teaching Hospital Fujita Health University School of Medicine

• WATANABE Shinya

  Department of Internal Medicine Second Teaching Hospital Fujita Health University School of Medicine

• TAKASHIMA Toshin

  Department of Internal Medicine Second Teaching Hospital Fujita Health University School of Medicine

Bibliographic Information

Other Title

• 集団検診において発見された胃食道逆流症 (特に, NERD) に関する検討
• シュウダン ケンシン ニ オイテ ハッケン サレタ イ ショクドウ ギャクリュウショウ トクニ NERD ニ カンスル ケントウ

Abstract

We studied the characteristics of gastroesophageal reflux disease (GERD) as discovered by a mass survey which lasted from November 2004 to September 2005. The subjects were 691 persons, each of whom underwent a medical examination by upper-gastrointestinal endoscopy at our medical examination center. There were 526 male and 165 female subjects, and their average age was 52.6 years. The incidence of reflux esophagitis and NERD was 12.2% and 10.4%, respectively.<BR>Using multivariable analysis, we investigated the factors which affect the onset of GERD. Young age (odds ratio: 0.40, 95% C. I.: 0.17-0.81, p<.05), female gender (odds ratio: 0.61, 95% C. I.: 0. 17-0.84, p<.05) and smoking (odds ratio: 1.95, 95% C. I.: 1.15-4.99, p<.05) were the risk factors of NERD. On the other hand, the risk factors of reflux esophagitis were esophageal hiatal hernia (odds ratio: 12.38, 95% C. I.: 6.41-21.0, p<.01), slight atrophy of the gastric mucosa (odds ratio: 0.14, 95% C. I.: 0.04-0.29, p<.01), male gender (odds ratio: 4.85, 95% C. I.: 1.17-7.97, p<.02) and obesity (odds ratio: 2.45, 95% C. I.: 1.01-3.44, p<.05). Because obesity and smoking were associated with the onset of reflux esophagitis and NERD, respectively, we concluded that GERD is one of the lifestyle-related diseases. It was suggested that the modification or eradication of certain habits might lead to the prevention of GERD.

Journal

• Nihon Shoukaki Gan Kenshin Gakkai zasshi

  Nihon Shoukaki Gan Kenshin Gakkai zasshi 44 (3), 283-291, 2006

  The Japanese Society of Gastroenterological Cancer Screening

Keywords

• GERD
• NERD

Details

• CRID: 1390282680429360000
• NII Article ID: 130004627278
• NII Article ID: 10018786101
• NII Book ID: AA12134881
• DOI: 10.11404/jsgcs2006.44.3_283
• NDL BIB ID: 8555317
• ISSN: 18807666
• Web Site: http://id.ndl.go.jp/bib/8555317
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I8555317
• Web Site: https://search.jamas.or.jp/link/ui/2006315868
• Text Lang: ja
• Data Source:
  • JaLC
  • NDL
  • CiNii Articles
• Abstract License Flag: Disallowed