下顎骨骨折術後に発症した横紋筋融解症の1例

  • 明石 靖史
    広島大学大学院・医歯薬学総合研究科・先進医療開発科学講座・分子口腔医学・顎顔面外科学
  • 谷 亮治
    広島大学大学院・医歯薬学総合研究科・先進医療開発科学講座・分子口腔医学・顎顔面外科学
  • 田中 良治
    広島大学病院歯系口腔総合診療科
  • 石田 康隆
    広島大学大学院・医歯薬学総合研究科・先進医療開発科学講座・分子口腔医学・顎顔面外科学
  • 虎谷 茂昭
    広島大学大学院・医歯薬学総合研究科・先進医療開発科学講座・分子口腔医学・顎顔面外科学
  • 岡本 哲治
    広島大学大学院・医歯薬学総合研究科・先進医療開発科学講座・分子口腔医学・顎顔面外科学

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タイトル別名
  • A case of rhabdomyolysis occurring after surgery for a mandibular fracture
  • ショウレイ ホウコク カガクコツ コッセツ ジュツゴ ニ ハッショウ シタ オウモンキン ユウカイショウ ノ 1レイ

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抄録

Rhabdomyolysis results from the release of skeletal muscle contents (myogloblin, creatinine kinase) and causes renal damage.<BR>We report a case of rhabdomyolysis that developed after a by mandibular fracture operation under general anesthesia.<BR>The patient was an 18-year-old man who underwent operation for surgical repositioning and fixation of the mandible, preformed under general anesthesia with sevoflurane. The course of anesthesia was uneventful, and the patient recovered uneventfully. Two hours postoperatively, dark red urine was voided. On the 1st postoperative day, the creatinine kinase (CK) was 38700 IU/I and increased further to 73900 IU/I at reexamination. He had tenderness of the right brachial muscle, and dark red urine presisted. Rhabdomyolysis caused by general anesthesia was diagnosed. The patient received an infusion of extracellular fluid, and CK normalized on the 11th postoperative day. As postoperative malignant hyperthermia (MH) was suspected, the Ca2 +-induced Ca2 +release (CICR) rate was examined. CICR was unaccelerated, ruling out a predisposition to MH. Seven months later, the fixation plates were removed with the patient under local anesthesia. There were no complications.

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