書誌事項
- タイトル別名
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- Tooth extraction under high-dose gamma-globulin therapy for patients with idiopathic thrombocytopepic purpura
- リンショウ トウケイ トクハツセイ ケッショウバン ゲンショウセイ シハンビョウ カンジャ ノ バッシ ニ オケル ガンマ グロブリン タイリョウ リョウホウ ノ ケントウ
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Idiopathic thrombocytopenic purpura (ITP) is an autoimmune disorder characterized by autoantibodies against platelets.<BR>It is necessary for patients with ITP to increase their platelet count before tooth extraction because of an increased risk of bleeding complications.<BR>In 1981 Imbach et al. reported that high-dose gamma-globulin therapy could increase the number of platelets in ITP.<BR>Recently, this treatment has been used clinically in the oral surgical field. However, there are no clinico-statistical reports.<BR>We clinically analyzed 12 patients with ITP who underwent tooth extraction under high-dose gamma-globulin therapy in our hospital from 1989 through 2004.<BR>The results were as follows:<BR>1. In 10 patients (83.3%), the platelet count increased to above 5×104/μ1. In 2 patients (16.7%), there was no elevation of the platelet level.<BR>2. There were no severe side effects associated with therapy.<BR>3. We consider high-dose gamma-globulin therapy very useful for increasing the platelet count immediately before tooth extraction in patients with ITP.
収録刊行物
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- 日本口腔外科学会雑誌
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日本口腔外科学会雑誌 52 (11), 629-633, 2006
社団法人 日本口腔外科学会
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詳細情報 詳細情報について
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- CRID
- 1390001206533415168
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- NII論文ID
- 10018859094
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- NII書誌ID
- AN00189163
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- ISSN
- 21861579
- 00215163
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- NDL書誌ID
- 8583443
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
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- 使用不可