A case of NK/T cell lymphoma in the upper jaw

DOI Web Site 7 Citations 12 References
  • IKEDA Tetsuya
    Department of Otorhinolaryngology, Oral Surgery, Kyorin University School of Medicine
  • MIYAZAWA Masazumi
    Department of Otorhinolaryngology, Oral Surgery, Kyorin University School of Medicine
  • KOHNO Naoyuki
    Department of Otorhinolaryngology, Oral Surgery, Kyorin University School of Medicine

Bibliographic Information

Other Title
  • 上顎に発生したＮＫ／Ｔリンパ腫の１例
  • ショウレイ ホウコク ジョウガク ニ ハッセイ シタ NK Tリンパ シュ ノ 1レイ

Search this article

Abstract

A 62-year-old man with an NK/T lymphoma originating in the right side of the upper jaw showed destruction of the hard palate and sino-nasal cavity. Intraoral examination revealed an ulcer with necrotic mucosa covering the area from the right side of the upper gingiva to the midline of the palate. CT scanning demonstrated a lesion on the right side of the sino-nasal cavity, and other clinical findings suggested a lethal midline granuloma. A biopsy specimen was positive for CD3, CD56, and Epstein-Barr virus (EBV), but negative for CD20. On the basis of these findings, a definitive diagnosis of NK/T lymphoma was established, and a course of radiation treatment was prescribed. Thereafter, his general condition deteriorated rapidly, and the patient died approximately 4 months later. In this disease, it is very difficult to establish a correct diagnosis. In situ hybridization study for EBV can contribute to the diagnosis because it can detect very small numbers of neoplastic cells in the early stage of disease.

Journal

Citations (7)*help

See more

References(12)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top