Staging System in Rapidly Destructive Coxarthrosis from Viewpoint of Synovial Osteoclast Activity

• Fujibayashi Isao

  Department of Orthopaedic Surgery, Faculty of Medicine, Saga University, Saga, Japan

• Ogawa Kenji

  Department of Orthopaedic Surgery, Faculty of Medicine, Saga University, Saga, Japan

• Kitajima Masaru

  Department of Orthopaedic Surgery, Faculty of Medicine, Saga University, Saga, Japan

• Shigematsu Masamori

  Department of Orthopaedic Surgery, Faculty of Medicine, Saga University, Saga, Japan

• Komine Mitsunori

  Department of Orthopaedic Surgery, Faculty of Medicine, Saga University, Saga, Japan

• Mawatari Masaaki

  Department of Orthopaedic Surgery, Faculty of Medicine, Saga University, Saga, Japan

• Hotokebuchi Takao

  Department of Orthopaedic Surgery, Faculty of Medicine, Saga University, Saga, Japan

Bibliographic Information

Other Title

• 急速破壊型股関節症の検討；第７報―病期分類と関節滑膜内破骨細胞数の関係について―
• ―病期分類と関節滑膜内破骨細胞数の関係について―

Abstract

To study the etiology and progress mechanisms of rapidly destructive coxarthrosis (RDC), we conducted a trial on type and staging system of RDC, taking into account the characteristics of radiographic and histological findings, and the activity of osteoclasts in synovial membrane.<BR>In this study, we investigated the association between the number of synovial osteoclasts and each stage in collapse type RDC.<BR>Fourteen hips with collapse type RDC and 33 hips with slowly progressive osteoarthritis as the control were analyzed.<BR>There was a significantly large number of synovial osteoclasts in stages II and III of collapse type RDC as compared to slowly progressive osteoarthritis.<BR>However, it was difficult to obtain the synovial tissues in stages I and IV of RDC.<BR>Our results suggest that osteoclasts may play a critical role in joint destruction, particularly in stages II and III of collapse type RDC.<BR>When investigating the etiology or pathologic mechanism of RDC, classifying the radiological and pathological findings according to type and staging should be cousidered.

Journal

• Orthopedics & Traumatology

  Orthopedics & Traumatology 56 (2), 267-269, 2007

  West-Japanese Society of Orthopedics & Traumatology

Keywords

• rapidly destructive coxarthrosis
• staging system
• osteoclast
• synovial membrane

Details

• CRID: 1390282679913071744
• NII Article ID: 130004460670
• NII Article ID: 10018917151
• NII Book ID: AN00126582
• DOI: 10.5035/nishiseisai.56.267
• ISSN: 13494333
• ISSN: 00371033
• Web Site: https://search.jamas.or.jp/link/ui/2007167636
• Text Lang: ja
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed