A Case of Follicular Lymphoma with Cutaneous Infiltration.

• NISHIE Wataru

  Division of Dermatology, Kin-I-kyo Central Hospital

• IITOYO Miyuki

  Division of Dermatology, Kin-I-kyo Sapporo Hospital

• ISHIHARA Toshimichi

  Division of Hematology, Kin-I-kyo Sapporo Hospital

• KANO Satoshi

  Division of Pathology, Kin-I-kyo Central Hospital

• SHIMIZU Michio

  Department of Pathology, Saitama Medical School

Bibliographic Information

Other Title

• 皮膚浸潤を生じたＦｏｌｌｉｃｕｌａｒ　Ｌｙｍｐｈｏｍａの１例

Abstract

A 62-year old woman with an ovarian tumor presented with indulated erythemas on her face, neck and back. A skin biopsy from a lesion on her back showed dense and nodular infiltrate of atypical mononucleocytes throughout the dermis. She underwent operation for the removal of the ovarian tumor and her pelvic and para-aorta lymph nodes. A histological examination of her para-aorta lymph node resulted in a diagnosis of follicular lymphoma (FL) of large cell type. Her ovaries also demonstrated a diffnse imfiltration of lymphoma cells in addition to the mucinous cystadenoma, endocervical type. These lymphoma cells showed CD3(-), CD10(+), CD20(+), CD5(-). Bcl-2 oncoprotein was only positive, however, at the cutaneous site. We discuss the prognostic factors of FL in association with both the histologic transformation into a diffuse pattern and the expression of bcl-2 protein in the secondary infiltrating lesions.

Journal

• Nishi Nihon Hifuka

  Nishi Nihon Hifuka 64 (2), 194-199, 2002

  Western Division of Japanese Dermatological Association

Keywords

• Dermatology

Details

• CRID: 1390282679276185728
• NII Article ID: 10018924918
• NII Book ID: AN00183881
• DOI: 10.2336/nishinihonhifu.64.194
• ISSN: 18804047
• ISSN: 03869784
• Web Site: https://search.jamas.or.jp/link/ui/2002208914
• Text Lang: ja
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed