A Case of Superficial Spreading Melanoma Developing in a Patient with Dysplastic Nevi.

DOI 36 References
  • SAITO Kenji
    Division of Dermatology, Nishinomiya Municipal Central Hospital
  • KOMURA Akihiko
    Division of Dermatology, Nishinomiya Municipal Central Hospital
  • UEDA Masato
    Department of Dermatology, Kobe University School of Medicine

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Other Title
  • Ｄｙｓｐｌａｓｔｉｃ　Ｎｅｖｕｓを有する患者に生じた表在拡大型悪性黒色腫の１例

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Abstract

We report a 34-year-old female patient presenting with malignant melanoma which was presumed to occur on a dysplastic nevus. Since adolescence she had multiple moles, two of them on the trunk and one on the lower leg which had recently increased in size. Two moles on the trunk were diagnosed to be dysplastic nevi clinicopathologically. The lesion on the lower leg showed malignant melanoma cells in the epidermis and the superficial dermis in continuity with nevus cells in the mid-dermis, giving a diagnosis of superficial spreading melanoma developing from dysplastic nevus. We furthermore surveyed 23 cases of melanoma associated with dysplastic nevus in Japanese and analyzed their clinicopathological features. The average age of the patient was 35 years old. These included 12 cases of superficial spreading melanoma and 8 cases of nodular melanoma, but no acral lentiginous melanoma was reported. Fifteen cases developed on trunk, 7 cases on the extremities and a case on face. A further compilation of Japanese cases is necessary to reveal the biological significance of dyplastic nevus in Japanese.

Journal

  • Nishi Nihon Hifuka

    Nishi Nihon Hifuka 64 (5), 581-585, 2002

    Western Division of Japanese Dermatological Association

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