COLLAGEN FIBER IN THE ARTICULAR DISC OF INFANT RAT TEMPOROMANDIBULAR JOINT

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  • 幼年期におけるラット顎関節円板の膠原線維について

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Abstract

Histological and immunohistochemical, and quantitative studies were done on the changes of cell density and the distribution area. Type I collagen and type III collagen in the articular disc of the infant rats temporomandibular disc related to aging. The articular discs of rat's were removed from new born animals, 7, 15 and 30 days after birth and were examined immumohistochemically. Quantitation of fibers was determined with the image analyzing system.<BR>From these observations we concluded that:<BR>1. The number of cells in articular disc decreased according to aging. Especially, the decreasing number is abrupt during 7 days after birth.<BR>2. Type I and III collagens were widely distributed in infant rat's articular disc.<BR>3. The distribution area of type I collagen of rat articular disc became smaller, in general, at a certain degree in accordance with aging. On the other hand, no remarkable changes were observed on the distribution area for type III collagen from the 3rd to the 15th day after birth.

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