糖タンパク質の運命を決定する細胞内レクチンの糖鎖認識

• Kamiya Yukiko

  Graduate School of Pharmaceutical Sciences, Nagoya City University

• Kato Koichi

  Graduate School of Pharmaceutical Sciences, Nagoya City University

書誌事項

タイトル別名

• Sugar Recognition by Intracellular Lectins That Determine the Fates of Glycoproteins
• トウ タンパクシツ ノ ウンメイ オ ケッテイ スル サイボウ ナイ レクチン ノ トウサ ニンシキ ガン エイブン

抄録

Accumulating evidence shows that the fates of glycoproteins in cells are determined through interactions of their carbohydrate moieties with a variety of intracellular lectins operating as molecular chaperones, cargo receptors, and ubiquitin ligases. Recent advances in developments of high-mannose type oligosaccharide libraries and structural biology of the carbohydrate-lectin interactions have revealed insights into sugar recognition by those intracellular lectins and the underlying mechanisms of quality control of glycoproteins. This article outlines the current knowledge on the molecular basis of sugar recognition by the intracellular lectins that control folding, transport, and degradation of glycoproteins in cells.

収録刊行物

• Ｔｒｅｎｄｓ　ｉｎ　Ｇｌｙｃｏｓｃｉｅｎｃｅ　ａｎｄ　Ｇｌｙｃｏｔｅｃｈｎｏｌｏｇｙ

  Ｔｒｅｎｄｓ　ｉｎ　Ｇｌｙｃｏｓｃｉｅｎｃｅ　ａｎｄ　Ｇｌｙｃｏｔｅｃｈｎｏｌｏｇｙ 18 (102), 231-244, 2006

  FCCA(Forum: Carbohydrates Coming of Age)

キーワード

• glycoprotein
• lectin
• glycosyltransferase
• folding
• transport
• degradation
• quality control

詳細情報

• CRID: 1390001204371550464
• NII論文ID: 130003698955
• NII論文ID: 10019281844
• NII書誌ID: AA10995236
• DOI: 10.4052/tigg.18.231
• COI: 1:CAS:528:DC%2BD28XhtVyqt7bP
• ISSN: 18832113
• ISSN: 09157352
• NDL書誌ID: 8076606
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I8076606
• Web Site: https://search.jamas.or.jp/link/ui/2007009886
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可