The Early Efficacy of Topical Levocabastine in Patients with Allergic Conjunctivitis
-
- Fujishima Hiroshi
- Department of Ophthalmology, Keio University School of Medicine
-
- Fukagawa Kazumi
- Department of Ophthalmology, Keio University School of Medicine
-
- Takano Yoji
- Department of Ophthalmology, Keio University School of Medicine
-
- Okamoto Shigeki
- Kozuka Eye Clinic
-
- Nakagawa Yayoi
- Nakagawa Eye Clinic
-
- Uchio Eiichi
- Department of Ophthalmology, Yokohama City University Medical Center
-
- Yokoi Norihiko
- Department of Ophthalmology, Kyoto Prefectural University of Medicine
-
- Fukushima Atsuki
- Department of Ophthalmology, Kochi Medical School
-
- Takamura Etsuko
- Department of Ophthalmology, Tokyo Women's Medical University
この論文をさがす
抄録
Background: We investigated the early efficacy of topical levocabastine, an H1 histamine-receptor antagonist, in improving the clinical symptoms of allergic conjunctivitis.<br> Methods: Thirty-six patients with allergic conjunctivitis were enrolled. One drop of levocabastine was instilled in one eye and one drop of artificial tears in the contralateral eye. Clinical examinations were performed before, and 15 and 30 minutes after instillation. Symptoms of itching and signs of injection were assessed at each time point.<br> Results: Both levocabastine and artificial tears resulted in a statistically significant reduction in ocular itching. However, levocabastine was significantly more effective.<br> Conclusions: Although artificial tears had a positive effect in reducing symptoms of allergic conjunctivitis, by the washing out of allergens, levocabastine was more effective than artificial tears in controlling acute symptoms of allergic conjunctivitis, demonstrating that the selective H1 histamine-receptor antagonist action of levocabastine is rapidly effective in a clinical setting.<br>
収録刊行物
-
- Allergology International
-
Allergology International 55 (3), 301-303, 2006
一般社団法人日本アレルギー学会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390282679607867904
-
- NII論文ID
- 130004476898
- 10019286577
-
- NII書誌ID
- AA11091750
-
- ISSN
- 14401592
- 13238930
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- Crossref
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可