卵巣組織の低温保存 Ovarian Tissue Banking

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Author(s)

    • 長谷川 昭子 HASEGAWA Akiko
    • 兵庫医科大学先端医学研究所発生・生殖部門 Laboratory of Developmental Biology and Reproduction, Institute for Advanced Medical Sciences
    • 霞 弘之 [他] KASUMI Hiroyuki
    • 兵庫医科大学先端医学研究所発生・生殖部門 Laboratory of Developmental Biology and Reproduction, Institute for Advanced Medical Sciences
    • 小森 慎二 KOMORI Shinji
    • 兵庫医科大学先端医学研究所発生・生殖部門 Laboratory of Developmental Biology and Reproduction, Institute for Advanced Medical Sciences
    • 香山 浩二 KOYAMA Koji
    • 兵庫医科大学先端医学研究所発生・生殖部門 Laboratory of Developmental Biology and Reproduction, Institute for Advanced Medical Sciences

Abstract

卵巣組織の凍結保存は、絶滅危惧生物の種の保全のみならずヒトの不妊症の治療にも有効な方法である。特にガン治療の結果、副作用として発症する卵巣機能障害および不妊症に対する対策として、その開発が望まれている。本稿では、ヒトおよび動物の卵巣組織の凍結保存の現状を紹介し、つぎにマウス凍結卵巣由来の前胞状期卵胞の発育誘導培養法と産仔への発育について述べる。

Ovarian tissue cryopreservation is an effective method for protecting against infertility as well as preservating endangered animal species. The technique is particularly sought after as a strategy against ovarian failure caused by aggressive chemotherapy in young women with cancer. There are two uses for cryopreserved ovarian tissues after thawing: grafting and culture. Grafting carries the risk of reintroduction of disease. This article describes the status of ovarian cryopreservation in humans and the other animals and also details the successful birth of a pup from preantral follicle oocytes derived from a mouse cryopreserved ovary followed by <i>in vitro</i> growth, <i>in vitro</i> maturation and <i>in vitro</i> fertilization-embryo transfer (IVF-ET).<br>

Journal

  • Journal of Mammalian Ova Research

    Journal of Mammalian Ova Research 24(1), 8-13, 2007-04-01

    JAPANESE SOCIETY OF OVA RESEARCH

References:  48

Codes

  • NII Article ID (NAID)
    10019488037
  • NII NACSIS-CAT ID (NCID)
    AN10548943
  • Text Lang
    ENG
  • Article Type
    REV
  • ISSN
    13417738
  • NDL Article ID
    8816541
  • NDL Source Classification
    ZR4(科学技術--生物学--動物)
  • NDL Call No.
    Z18-1673
  • Data Source
    CJP  NDL  J-STAGE  JASI 
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