Effects of Dietary Protein and Peptide on Recovery from Iron Deficiency Anemia by Rats

• Kobayashi Yukiko

  Department of Food Sciences and Nutritional Health, Faculty of Human Environment, Kyoto Prefectural University

• Kido Yasuhiro

  Department of Food Sciences and Nutritional Health, Faculty of Human Environment, Kyoto Prefectural University

• Nakabou Yukihiro

  Department of Food Sciences and Nutritional Health, Faculty of Human Environment, Kyoto Prefectural University

Bibliographic Information

Other Title

• 鉄欠乏性貧血ラットの回復期における食事たんぱく質およびペプチドの影響
• テツ ケツボウセイ ヒンケツ ラット ノ カイフクキ ニ オケル ショクジ タンパクシツ オヨビ ペプチド ノ エイキョウ

Abstract

Iron deficiency anemia has been reported to be the most frequent symptom in young adult women. The aim of this study was to verify in iron-deficient rats the efficacy of dietary protein or peptide and the time-course characteristics of recovery from iron deficiency anemia. Rats made anemic by iron-deficient diets for 3 weeks were given egg white protein (EW), egg white peptide (EWP), soy protein isolated (SPI) and soy protein isolated peptide (SPIP) diets with equivalent amounts of protein (N×6.25) and iron (ferric citrate) for 2 weeks. No recovery of hemoglobin concentration from anemia was evident after 2 weeks of treatment with any of the protein or peptide sources. However, the increase of iron in the plasma and hepatic tissue of rats fed with the EW diet was significantly greater than that of the rats fed with the SPI, EWP and SPIP diets. Moreover, after an intragastric administration to normal rats of the EW or EWP solution with an equivalent amount of ferric citrate, the ratio of Fe²⁺ ions to total iron in the gastrointestinal tract of the rats fed with EW was higher than that in the rats fed with EWP. These results suggest that egg white protein was useful to the process of recovery from iron deficiency anemia due to the improved absorption and utilization of iron.

Journal

• The Japanese Journal of Nutrition and Dietetics

  The Japanese Journal of Nutrition and Dietetics 65 (4), 165-171, 2007

  The Japanese Society of Nutrition and Dietetics

Keywords

• recovery from anemia
• egg white protein
• egg white peptide
• iron-deficient rat

Details

• CRID: 1390001206549158016
• NII Article ID: 130003667905
• NII Article ID: 10019512897
• NII Book ID: AN00023058
• DOI: 10.5264/eiyogakuzashi.65.165
• ISSN: 18837921
• ISSN: 00215147
• NDL BIB ID: 8928676
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I8928676
• Web Site: https://search.jamas.or.jp/link/ui/2008008554
• Text Lang: ja
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed