Ｂｒｕｎｎｅｒ腺由来が示唆された早期十二指腸癌の１例

DOI 被引用文献5件 参考文献20件

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  • A CASE OF PRIMARY DUODENAL CANCER SUSPECTED OF BEING DERIVED FROM BRUNNER'S GLANDS FROM HISTOPATHOLOGICAL FINDINGS

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Primary duodenal cancer has been increasingly reported with recent advances in imaging techniques. It has been considered that cancers very rarely arise from the duodenal(Brunner's) glands, however, anecdotal reports indicate recent cases in Japan. We report a case with characteristic histopathological findings, which was considered to be duodenal cancer derived from Brunner's glands. A 77-year-old male visited our hospital with a chief complaint of tarrystool. Ulcerative lesions with exposed blood vessels on the posterior wall of the stomach were seen by upper GI endoscopy performed on the same day, and he underwent conservative management. Endoscopic examination was subsequently performed, and 15 mm elevated lesions with depressed surface were confirmed in the descending duodenum. Biopsies of the depressed lesions lead to strong suspicion of adenocarcinoma. After informed consent was obtained, en bloc resection was performed using the strip biopsy method according to the stomach EMR. Histopathological examination of the resected specimen revealed duodenal cancer with sm invasion. Normal Brunner's glands, Brunner's glands hyperplasia, and adenocarcinoYna were mixedely noted by iinmunohistological examination on the resected specimen, therefore duode-num cancer derived from Brunner's glands was suspected, and was considered to be an impor-tart case.

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