Effect of Fatty Acids on Interaction between Liposome and Amyloid β-peptide

• Morita Seiichi

  Department of Materials Science, Wakayama National College of Technology

• Hamano Yuya

  Department of Materials Science, Wakayama National College of Technology

• Kuboi Ryoichi

  Department of Chemical Science and Engineering, Graduate School of Engineering Science, Osaka University

Bibliographic Information

Other Title

• Effect of fatty acids on interaction between liposome and amyloid v peptide

Abstract

In 1, 2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC)/fatty acid (FA) system, the analysis of the interaction between the DMPC/FA liposome and amyloid β-peptide (Aβ) was carried out by using the quartz crystal microbalance (QCM) method, together with the analysis of the compression isotherms of the DMPC/FA monolayer. The DMPC/stearic acid (SA) liposome showed the highest intensity in its interaction with Aβ through the QCM method although the slight interaction between DMPC/linoleic acids (LAs) liposome and Aβ was obtained. The compression isotherm analysis of the lipid monolayers revealed that the DMPC/SA monolayers underwent the distinct phase transfer, with which the interaction between both molecules changed from repulsive to attractive, while DMPC/linoleic acid monolayers did not.

Journal

• MEMBRANE

  MEMBRANE 32 (4), 215-220, 2007

  THE MEMBRANE SOCIETY OF JAPAN

Keywords

• lipidmembrane-amyloidβ-peptideinteraction
• liposome-immobilized quartz crystal microbalance
• compression isotherm
• phase transfer

Details

• CRID: 1390282681399598080
• NII Article ID: 10019583144
• NII Book ID: AN0023215X
• DOI: 10.5360/membrane.32.215
• ISSN: 18846440
• ISSN: 03851036
• NDL BIB ID: 8905527
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I8905527
• Web Site: https://www.jstage.jst.go.jp/article/membrane/32/4/32_215/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2008033363
• Text Lang: en
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed