Studies on the structure and function of phytochromes as photoreceptors based on synthetic organic chemistry

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  • Award accounts: The Chemical Society of Japan Award for Creative Work for 2006: Studies on the structure and function of phytochromes as photoreceptors based on synthetic organic chemistry

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We developed an efficient and flexible general method for the preparation of linear tetrapyrrole (bilin) chromophores of phytochromes as photoreceptors, including sterically locked derivatives as photoreceptors. Assembly experiments of the synthesized chromophores with apophytochromes in vitro and in vivo provided us insights into the structure and function of phytochromes. An efficient and flexible synthetic method of phytochrome chromophores was developed. Assembly experiments of the synthetic chromophores with apophytochromes in vitro and in vivo provided us insights into the structure and function of phytochromes as photoreceptors. Fullsize Image

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